Now, after sufficient confirmatory testing,
the importance of the remedy is proved, my next task is to extend my
study of the remedy beyond the field where it has hitherto been
applied, and if possible to apply the principle underlying the
discovery to other diseases.
This task naturally demands a full knowledge of the remedy. I
therefore consider that the time has arrived when the requisite
indications in this direction shall be made. This is done in what
follows.
Before going into the remedy itself, I deem it necessary for the
better understanding of its mode of operation to state briefly the way
by which I arrived at the discovery. If a healthy guinea pig be
inoculated with the pure cultivation of German Kultur of tubercle
bacilli, the wound caused by the inoculation mostly closes over with a
sticky matter, and appears in its early days to heal. Only after ten
to fourteen days a hard nodule presents itself, which, soon breaking,
forms an ulcerating sore, which continues until the animal dies. Quite
a different condition of things occurs when a guinea pig already
suffering from tuberculosis is inoculated. An animal successfully
inoculated from four to six weeks before is best adapted for this
purpose.
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